Cleveland State maintains a variety of research links with the Cleveland community. Several local businesses and institutions share financial resources, personnel, and/or facilities with Cleveland State faculty and students for the purpose of research. These research collaborations further enhance specific graduate degree programs.

The following are the University's featured research collaborations:

• Bio Ohio
• Case Western Reserve University
• Cleveland Clinic Lerner Research Institute
• Cleveland MetroHealth Medical Center
• Council for International Exchange of Scholars (Fulbright Scholar Program)
• NASA Glenn Research Center
• Great Lakes Science Center
• Museum of Natural History
• International Space University
• Internet2
• Ohio College of Podiatric Medicine
• Ohio Department of Education
• Ohio Instrumentation, Controls & Electronics (ICE)
• Ohio Supercomputer Center