Northeastern Ohio Section Young Scientist Awards
Cash prizes for grades 9-12 students.
Presentation of the Edward W. Morley Award and Address
Wednesday, May 16, 2018
Michaelson & Morley Restaurant
11038 Bellflower Rd., Cleveland, OH 44106
|4:30 pm Executive Committee Meeting
5:00 pm Social/Networking
5:45-7:00 pm Dinner
7:00 pm Award presentation and Address
"Some chemical and biological highlights of nitric oxide production by mammals"
Dr. Dennis J Stuehr, Professor, Dept. Molecular Medicine, Cleveland Clinic Lerner Case Western Reserve University School of Medicine and Full Staff, Dept. Pathobiology, Lerner Research Inst., Cleveland Clinic Foundation
That mammals might synthesize nitrogen oxides was first suspected in the late 1800’s, but remained controversial until experiments could finally be done using germ-free animals around 1980. While this early work was forging a clear tie between nitrogen oxide biosynthesis and stimulation of the mammalian immune system, parallel work was discovering a role for nitric oxide (NO) as a signal molecule for vascular relaxation in the mammalian circulatory system. These and related discoveries fueled a tremendous interest that led to the awarding of the 1998 Nobel prize in Physiology & Medicine for NO research, and the current publication of more that 6000 papers/year on NO biochemistry and biology. Mammals express three related NO synthase enzymes (NOSs) that each generate NO from the amino acid L-arginine under various biological settings and circumstances. Although NOSs are heme-containing enzymes whose catalysis is broadly similar to the cytochrome P450 enzymes, they have evolved separately and display some unique and interesting facets regarding their structure, reaction chemistry, cofactor use, and regulation. The Morley talk will highlight these unique aspects, and will specifically address how NOS enzymes catalyze an odd-electron chemistry to generate NO as their free radical product, and the “tricks” that NOS enzymes use to insure that their catalysis can go on, despite it generating a potent heme poison (NO) as a product.
A Please RSVP to Drew Meyer by email at firstname.lastname@example.org with
the names and number of people in your party by Wednesday, May 9,
2018. Dinner will include choice of :
Pan seared scallops/cauliflower puree/roasted grapefruit/fennel/orange reduction
Maple brined chicken/sweet potato risotto/brocoli rabe/roasted chicken demi
Skirt steak/carboanara dumplings/baby spinach/mustard jus
Vegetable lo- mein/ vegetables/ crispy tofu /mushroom miso broth/cashews.
The ACS accepts credit cards, cash, and/or checks made
out to “Cleveland ACS.” Cost: $20 for members & guests; $10 for retirees & unemployed; $5 for students.
The Social Hour and Dinner will be in the Michelson & Morley Restaurant
in the Tinkham Veale University Center on the campus of Case Western
Reserve University. Parking may be obtained in the Severance Hall garage,
entrance off East Boulevard, and there is an entrance to the Tinkham Veale
Center from the garage. (On street parking may also be available.) The
Award Presentation and Seminar will immediately follow dinner and be in
the Thwing Center located next door to the Tinkham Veale University
held Wednesday, Mar. 28, 2018
Program details may be found here.
Congratulations to our student award winners
Graduate Awards (Sponsors: Amalgamated Tuna Co., Dwight Chasar, Lubrizol Corporation)
Ashraf Duzan, Cleveland State University
Kevin Pachuta, Case Western Reserve University
Jerod M. Kieser, Case Western Reserve University
Undergraduate Awards (Sponsors: Amalgamated Tuna Co., Energizer Battery Inc., Oberlin College Department of Chemistry)
Leéna Boone, Lorain County Community College
Huan Kyle Nguyen, College of Wooster
P. A. Advincula, Case Western Reserve University
Important Update from the Cleveland Section
With support from an ACS grant we have begun a strategic planning exercise. Please click here for an article detailing the strategic planning retreat held Oct. 10-11, 2015
ACS Cleveland Section
PO Box 5497